Considerations To Know About ceesdekker
Considerations To Know About ceesdekker
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Human Rad51 filaments on double- and solitary-stranded DNA: correlating regular and irregular kinds with recombination functionality.
[Laughs] ‘It had been undoubtedly a fantastic danger! At the time, I was perfectly knowledgeable that it could go Erroneous Which I could grow to be much less successful, but I just disregarded that. Curiosity has generally been my strongest driving pressure. And fortuitously it all labored out.’
Sculpting nano-electrodes by using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Our exploration ranges with the biophysics of DNA to synthetic cells and beyond. Please have a look down below within the spectrum of our present-day jobs.
‘In the beginning we checked out Organic methods by using a Actual physical see and acted on The idea with the tools we knew. It took a several years right before we began Functioning additional on the massive Organic problems. I then started to phone it nanobiology, a time period that didn't exist at time.
2011, very first in vitro measurements of transport across a single biomimetic nuclear pore complex; development of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
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Bulk-area coupling identifies the mechanistic connection among Min-protein designs in vivo As well as in vitro
[fourteen] In 2005 Dekker became involved with Netherlands-wide conversations about Clever Design and style, a motion that he has because Plainly distanced himself from. Dekker advocates that science and religion will not be in opposition but can be harmonized.
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2008, 1st observation of protein-coated DNA translocation by way of nanopores; solved the origin on the electrophoretic power on DNA in nanopores; identified a major velocity boost of microtubules in electrical fields; uncovered an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid
2004, discovery of recent physics in translocation of DNA by nanopores; very first experimental research of ions conduction in nanofluidic channels; to start with electrochemistry with specific single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and first solitary-molecule study of DNA translocation by a restriction-modification enzyme.